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Title
Celiac Disease Insights: Clues to Solving Autoimmunity
Milk Thistle Compound plus Vitamin E Benefits Patients with Hepatitis C
Homocysteine, Cortisol, and Vitamin C (Ascorbate)
Mortality in patients with celiac disease and their relatives: a cohort study
Mechanisms underlying celiac disease and its neurologic manifestions
Supplementation with Vitamin D May Reverse Myalgia in Statin-treated Vitamin D Deficient Patients
Folic Acid Supplementation Before Conception May Increase Fetal Growth

Title: Celiac Disease Insights: Clues to Solving Autoimmunity ( Preview )
Reference: Scientific American, Aug 2009
Summary: Study of a potentially fatal food-triggered disease has uncovered a process that may contribute to many autoimmune disorders. Read the full article

Title: Milk Thistle Compound plus Vitamin E Benefits Patients with Hepatitis C
Reference: "Treatment with silybin-vitamin E-phospholipid complex in patients with hepatitis C infection," Falasca K, Ucciferri C, et al, J Med Virol, 2008; 80(11): 1900-6. (Address: Jacopo Vecchiet, Clinic of Infectious Diseases, Department of Medicine and Science of Aging, G. D'Annunzio University, School of Medicine, Via dei Vestini, Chieti 66100, Italy. E-mail: Jacopo Vecchiet, jvecchiet@unich.it ).
Summary: In a study with 40 patients, that the use of Vitamin E and Milk Thistle for 3 mos greatly reduced liver functions, inflammation,C-reactive protein, glucose, and cholesterol levels. These were patients with chronic Hepatitis C who could not undergo conventional antiviral therapy.

Title: Homocysteine, Cortisol, and Vitamin C (Ascorbate)
Reference: "Serum homocysteine: relationship with circulating levels of cortisol and ascorbate," Cascalheira JF, Parreira MC, et al, Ann Nutr Metab, 2008; 53(1): 67-74. (Address: Health Sciences Research Center, University of Beira Interior, Covilhã, Portugal. E-mail: jfcascalheira@ubi.pt ).
Summary: This study of 60 patients over the age of 50 showed that high levels of homocysteine increases with age and with an elevated cortisol level. Also found that (not surprising) with a high homocysteine, levels of folate were very low. High cortisol showed low levels of ascorbate or Vitamin C. Additional research needs to be done to prove Vitamin C may reduce homocysteine and cortisol levels.

Title: Mortality in patients with celiac disease and their relatives: a cohort study.
Reference: Lancet .Vol 358, August 4, 2001
Summary: This is an old study but very impactful: This study showed that if you compared 2 relatives both with celiac, one who is very strict and the other eats gluten once a month, there is a increased risk of death for the ones who consume gluten once a month, by 600%!

Title: Mechanisms underlying celiac disease and its neurologic manifestions
Reference: CMLS, Cell Mol Life Sci. 62 (2005) 791-799.
Summary: This study shows that a gluten free diet may improve neurologic, cardiac, and renal diseases.

Title: Supplementation with Vitamin D May Reverse Myalgia in Statin-treated Vitamin D Deficient Patients
Reference:  
Summary: In a study involving 621 patients treated with statin drugs like Lipitor, those who were experiencing myalgia or muscle pain ,were found to have lower serum vitamin D levels , as compared to asymptomatic patients not experiencing myalgia. Low serum levels of vitamin D were found in 64% of patients with myalgia, as compared to 43% of asymptomatic patients. When thirty eight of the myalgic patients with vitamin D deficiency were given vitamin D, a resolution of mylagia was found in 92% of subjects, and serum vitamin D levels increased from 20.4 to 48.2 ng/mL. The authors conclude, "We speculate that symptomatic myalgia in statin-treated patients with concurrent vitamin D deficiency may reflect a reversible interaction between vitamin D deficiency and statins on skeletal muscle."

Title: Folic Acid Supplementation Before Conception May Increase Fetal Growth
Reference:  
Summary: In a study involving 6,353 pregnancies, results indicate that periconception folic acid supplementation may be associated with higher placental weight and higher birth weight. Periconception supplementation with 400-500 micrograms of folic acid was associated with 68 g higher birth weight and 13 g higher placental weight, compared with no supplementation. Periconception folic acid supplementation was associated with a 57% reduced risk of low birth weight and a 60% reduced risk of small for gestational age, compared with no folic acid supplementation. Thus, the authors of this study conclude, "periconception folic acid supplementation is associated with increased fetal growth resulting in higher placental and birth weight, and decreased risks of low birth weight and SGA."
   
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